Download Adult Stem Cells by Kursad Turksen (eds.) PDF

By Kursad Turksen (eds.)

ISBN-10: 1461495687

ISBN-13: 9781461495680

ISBN-10: 1461495695

ISBN-13: 9781461495697

Adult Stem Cells, moment version, takes a severe examine concerns in regards to the developmental or differentiation strength for a number of tissue varieties and for particular grownup stem telephone varieties. because the first variation seemed a decade in the past, our knowing of grownup stem cells, and extra in particular tissue-specific grownup stem cells, has complex enormously. And an elevated curiosity in regenerative medication and capability stem phone purposes has pushed a quest for larger knowing of stem mobile biology. In flip, this has spawned a lot job on new release and usage of extra and higher reagents to spot and isolate stem cells and stem cell-like subpopulations, and on assays elucidating their developmental or differentiation capability and useful integration with host tissues and organs.

In this absolutely up to date new version, chapters hide issues starting from signaling pathways protecting stemness in hematopoietic cells to regeneration after damage and endocrine mechanisms underlying the stem mobile conception of getting older. different chapters hide stem cells through organ or procedure together with pituitary, cardiac, epithelial, the teeth, lung, ovary, prostate, liver, and lots of extra. Importantly, the authors of the chapters haven't in simple terms summarized their successes, yet have additionally summarized a number of the problems that every specific box continues to be dealing with with appreciate to maximizing the software of stem cells in medical settings. jointly, they communicate either the thrill and demanding situations dealing with stem mobile usage for fix and regeneration making this publication crucial examining for these considering stem telephone learn in addition to these all for medical assays.

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Extra resources for Adult Stem Cells

Sample text

However, although blood vessel associated, there is no evidence that myoendothelial cells can transmigrate to skeletal muscle if transplanted systemically. 3 Pericytes/Mesoangioblasts Myogenic cells derived from the mouse embryonic dorsal aorta, which co-expressed endothelial and myogenic markers, were shown to contribute to skeletal muscle growth and regeneration [68]. These cells, termed mesoangioblasts, are multipotent stem cells [69], able to differentiate into several mesodermal tissues and might be the origin of postnatal mesodermal stem cells.

J Exp Med 127(1):205–214 9. Schofield R (1978) The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 4(1–2):7–25 10. Barker JE (1994) Sl/sld hematopoietic progenitors are deficient in situ. Exp Hematol 22(2):174–177 11. Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MA, Werb Z, Rafii S (2002) Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand.

Cell 131(2):324–336 28 A. Ramakrishnan et al. 39. Roecklein BA, Torok-Storb B (1995) Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes. Blood 85(4): 997–1005 40. Graf L, Iwata M, Torok-Storb B (2002) Gene expression profiling of the functionally distinct human bone marrow stromal cell lines HS-5 and HS-27a. Blood 100(4):1509–1511 41. Pillai MM, Yang X, Balakrishnan I, Bemis L, Torok-Storb B (2010) MiR-886-3p down regulates CXCL12 (SDF1) expression in human marrow stromal cells.

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Adult Stem Cells by Kursad Turksen (eds.)

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